
Bio Imaging
Having grown up with a parent who did biological research, I learned to speak biology as a youngster. I have found there is a rich interface of research and development between the fields of optics and biology where a lot can be learned and shared.
Much of my research of the past 2 decades has been related to the imaging of biological samples.
In the early 2000's I worked on low-light level imaging of bio processes showing that you can image low-level self bio-luminescence without the use of fluorescent markers.
Between 2009-2014 I worked with 4D Technology to develop a commercial instrument based upon a Linnik interference microscope using dynamic quantitative phase-measuring microscopy (QPM) in real-time.
The animated image above shows real-time beating of live cardiac myocytes grown on a slide and imaged using the QPM described above. This truly was a wonder to discover that we could image these kinds of cellular contractions without the use of any toxic dyes or fluorescent markers.
My goal in these endeavors has been to work toward non-invasive imaging techniques to image and monitor cellular processes. There is still a ways to go before these imaging systems are mainstream.
In today's world, to get these types of new technologies adopted we need to interface them with techniques that the biology community is already familiar with.
I can help you move your systems in that direction.